Experimental infection with a low virulence isolate ofNeospora caninumat 70 days gestation in cattle did not result in foetopathy

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Experimental infection with a low virulence isolate of Neospora caninum at 70 days gestation in cattle did not result in foetopathy

The Nc-Spain 1H isolate of Neospora caninum, which was newly obtained from the brain of a congenitally asymptomatic infected calf, demonstrated a reduced in vitro tachyzoite yield and viability rate, as well as low virulence in mouse models. The objective of the present study was to determine the ability of this isolate to induce foetal death in a pregnant bovine model. For this purpose, 13 naï...

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Effect of vaccination of cattle with the low virulence Nc-Spain 1H isolate of Neospora caninum against a heterologous challenge in early and mid-gestation

Live vaccines have emerged as one of the most potentially cost-effective measures for the control of bovine neosporosis. Previous studies have shown that Nc-Spain 1H is a naturally attenuated isolate of Neospora caninum and that immunisation with live Nc-Spain 1H tachyzoites generated a protective immune response in mice. The aim of this study was to evaluate the safety and efficacy of immunisa...

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Managing gestation in cattle

Once a cow becomes pregnant, the effect of pregnancy loss on its reproductive cycle is a topic of great interest for dairy herds. This paper reviews the factors of a non-infectious nature that affect the pregnancy maintenance during the late embryonic/early fetal period. Some clinical suggestions on bovine neosporosis and coxiellosis are also highlighted.

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Mesenteric lymph nodes infection with Linguatula serrata nymphs in cattle

871 mesenteric lymph nodes taken from 110 native cattle from Urmia slaughter-house with differentages were examined for Linguatula serrata infection. The lymph nodes were studied based on their colourand consistency. 44% of the cattle were found positive for L. serrata infection. The number of parasitesisolated from each infected lymph node varied from 1 to 69 with a mean of 5.48. There were no...

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Maternal and foetal immune responses of cattle following an experimental challenge with Neospora caninum at day 70 of gestation

The immune responses of pregnant cattle and their foetuses were examined following inoculation on day 70 of gestation either intravenously (iv) (group 1) or subcutaneously (sc) (group 2) with live NC1 strain tachyzoites or with Vero cells (control) (group 3). Peripheral blood mononuclear cell (PBMC) responses to Neospora antigen and foetal viability were assessed throughout the experiment. Two ...

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ژورنال

عنوان ژورنال: Veterinary Research

سال: 2009

ISSN: 0928-4249,1297-9716

DOI: 10.1051/vetres/2009032